What are adaptive designs in sequential testing?

What are adaptive designs in sequential testing?

Adaptive designs in sequential testing allow researchers to modify trial parameters based on interim results.

Can you give me an example of how this works in a clinical trial?

Sure! In a clinical trial, if early results show a treatment is effective, the trial can be adapted to enroll more patients.

What are the benefits of using adaptive designs?

Benefits include increased efficiency, ethical considerations by reducing patient exposure to ineffective treatments, and faster decision-making.

Are there any challenges associated with adaptive designs?

Yes, challenges include complexity in design, regulatory considerations, and the need for robust statistical methods.