What are enzyme inhibitors and how were they discovered?

What are enzyme inhibitors and how were they discovered?

Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. They were discovered through various biochemical studies, particularly in the early 20th century.

Can you give me an example of a well-known enzyme inhibitor?

Sure! One well-known enzyme inhibitor is aspirin, which inhibits the enzyme cyclooxygenase, reducing inflammation and pain.

How do scientists identify new enzyme inhibitors?

Scientists often use high-throughput screening methods to test thousands of compounds for their ability to inhibit specific enzymes.

What are the applications of enzyme inhibitors in medicine?

Enzyme inhibitors are used in various medications, including those for hypertension, cancer, and infectious diseases, to regulate enzyme activity.

Are there any side effects associated with enzyme inhibitors?

Yes, enzyme inhibitors can have side effects, which vary depending on the specific inhibitor and the individual, including allergic reactions or interactions with other medications.