What are enzyme inhibitors and how do they work?

What are enzyme inhibitors and how do they work?

Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. They can be competitive, non-competitive, or uncompetitive.

Can you explain the difference between competitive and non-competitive inhibitors?

Sure! Competitive inhibitors bind to the active site of the enzyme, preventing substrate binding. Non-competitive inhibitors bind to a different site, reducing the enzyme's activity regardless of substrate presence.

What are some examples of enzyme inhibitors in medicine?

Examples include statins, which inhibit HMG-CoA reductase to lower cholesterol, and ACE inhibitors, which help manage blood pressure.

How do enzyme inhibitors affect metabolic pathways?

Enzyme inhibitors can alter metabolic pathways by slowing down or blocking specific reactions, which can impact overall metabolism and homeostasis.