What is the mechanism of inhibition in biochemistry?
The mechanism of inhibition refers to how certain molecules can decrease or stop the activity of enzymes or receptors.
Can you explain the different types of inhibition?
Sure! There are two main types: competitive inhibition, where an inhibitor competes with the substrate for the active site, and non-competitive inhibition, where the inhibitor binds to a different site, altering the enzyme's function.
How does competitive inhibition affect enzyme activity?
In competitive inhibition, the presence of the inhibitor reduces the rate of reaction by competing with the substrate, which can be overcome by increasing substrate concentration.
Are there any real-world examples of competitive inhibitors?
Yes, a common example is the drug methotrexate, which inhibits the enzyme dihydrofolate reductase, used in cancer treatment.
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