What is the difference between reversible and irreversible inhibition?

What is the difference between reversible and irreversible inhibition?

Reversible inhibition occurs when an inhibitor binds to an enzyme temporarily, while irreversible inhibition involves permanent binding.

Can you give examples of each type?

Sure! An example of reversible inhibition is competitive inhibition, where the inhibitor competes with the substrate. An example of irreversible inhibition is the binding of aspirin to cyclooxygenase.

How do these types of inhibition affect enzyme activity?

Reversible inhibitors can be removed, allowing enzyme activity to resume, while irreversible inhibitors permanently deactivate the enzyme.

Are there any practical applications for these inhibitors?

Yes, reversible inhibitors are often used in drug design to regulate enzyme activity, while irreversible inhibitors can be used in pesticides and antibiotics.