What role do enzyme inhibitors play in drug development?

What role do enzyme inhibitors play in drug development?

Enzyme inhibitors are crucial in drug development as they can block specific enzymes involved in disease processes, helping to treat various conditions.

Can you give me an example of a drug that uses enzyme inhibitors?

Sure! One well-known example is aspirin, which inhibits the enzyme cyclooxygenase to reduce pain and inflammation.

How do researchers determine which enzymes to target?

Researchers often study the biochemical pathways involved in diseases to identify key enzymes that, when inhibited, can alter disease progression.

Are there any side effects associated with enzyme inhibitors?

Yes, enzyme inhibitors can have side effects, as they may also affect normal physiological processes, leading to unintended consequences.

What are the challenges in developing enzyme inhibitors?

Challenges include specificity, as inhibitors must target only the intended enzyme without affecting others, and potential resistance.